FIRST CLINICAL EXPERIENCE WITH FRACTIONATED INTRACAVITARY RADIOIMMUNOTHERAPY USING [177LU]LU-6A10-FAB FRAGMENTS IN PATIENTS WITH GLIOBLASTOMA: A PILOT STUDY

Abstract Background Following resection and standard adjuvant radio- and chemotherapy, approved maintenance therapies for glioblastoma are lacking.Intracavitary radioimmunotherapy (iRIT) with 177Lu-labeled 6A10-Fab fragments targeting tumor-associated carbonic anhydrase XII and injected into the resection cavity offers a novel and promising strateg

Abstract Background In North America, opioid use has become a public health crisis with policy makers declaring it a state of emergency.Opioid substitution therapy (OST) is a harm-reduction method used in treating opioid use disorder.While OST has shown to be successful in improving treatment outcomes, there is still a great degree of variability a

Urinary incontinence is a bothersome situation to the ailing woman.Many times, the woman does not come to medicos due to shyness, and if she comes also she does not reveal all the information.Hence, a sympathetic and structured approach will help to provide judicious management to these women.When a woman with the complaint of urinary incontinence

Two kinetic models were established for conservative estimates of photodegradation rates of contaminants under sunlight irradiation, in particular for wastewater stabilisation ponds Backpack and clarifiers in conventional wastewater treatment plants.These two models were designated for (1) contaminants with high photolytic rates or high photolytic